Promoted Frosinone host a Sassuolo side without Leysen
Frosinone welcome Sassuolo to the Stadio Benito Stirpe on Friday, 16 October 2026, in the seventh round of Serie A. Promoted Frosinone are ninth with ten points, two more than Sassuolo, who are 11th. The two sides met in the Coppa Italia in September, when Sassuolo went through on penalties after a 1-1 draw. Kick-off is at 20:45, with Matteo Marchetti the referee.
“Il Frosinone sta facendo un percorso eccezionale.” – Frosinone manager Massimiliano Alvini
Predicted lineups: Frosinone vs Sassuolo
Sassuolo confirmed on Wednesday that centre-back Fedde Leysen has torn the anterior cruciate ligament in his left knee, an injury he suffered against Milan. Cas Odenthal, who came on for him and scored the equaliser, is expected to start alongside Duje Ćaleta-Car. Jay Idzes, Daniel Boloca and Ismaël Koné are also unavailable. Frosinone are without Florian Grillitsch and Daniel Bîrligea, but striker Antonio Raimondo, who hit the woodwork twice at Napoli, is expected to be fully fit.
Frosinone Team News & Preview
Frosinone have made an impressive start after promotion, with three wins from six games and a goal difference of 9:7. At home they have beaten Venezia 3-2 and Como 2-0, losing only 1-0 to Juventus, and they also won 3-0 at Fiorentina. Their last game was a 3-0 defeat at Napoli, but Alvini felt the scoreline was harsher than the performance, and Raimondo struck the woodwork twice in the second half.
Raimondo leads the scoring with four league goals, and Giorgi Kvernadze has three. Frosinone have kept two clean sheets, and only two of their six league games have seen both teams score.
What works for or against Frosinone
- Two wins from three home league games.
- Raimondo has four league goals and hit the woodwork twice at Napoli.
- Lost 3-0 at Napoli last time out.
- Grillitsch and Bîrligea are injured.
Sassuolo Team News & Preview
Sassuolo have eight points from six games, with wins over Torino and Juventus at home. Away from home it is a different picture: they lost 2-1 at Atalanta, drew 2-2 at Bologna and lost 2-1 at Monza. On Sunday they drew 1-1 with Milan, Odenthal scoring from a corner five minutes after Rabiot had given Milan the lead.
The loss of Leysen is a blow to Alberto Aquilani’s back line, and Sassuolo have not kept a clean sheet in Serie A this season. In attack, Domenico Berardi remains the key creator, and Vasilije Adžić is their top league scorer with three goals.
What works for or against Sassuolo
- Drew 1-1 with Milan and beat Juventus 3-2 at home.
- Berardi gives them quality on the right.
- No away win in three league games.
- No clean sheet in six league games, and Leysen now out long-term.
Frosinone vs Sassuolo Odds
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Frosinone Form, Stats & Data
Frosinone score 1.5 goals and concede 1.17 per league game. Alvini’s side are compact and well organised in a 4-2-3-1, and at home they have shown they can beat sides of Sassuolo’s level.
Sassuolo Form, Stats & Data
Sassuolo score and concede 1.67 goals per league game. They are dangerous at home, but their away record is poor, and losing Leysen weakens a defence that has conceded in every league game.
Frosinone vs Sassuolo: Prediction & Betting Tip
Frosinone have been strong at home, with two wins from three, while Sassuolo have not won away from home in the league. Sassuolo also arrive without Leysen, and they have conceded in all six of their league games. I like Frosinone here, and Draw No Bet gives me protection against a draw, which is a real possibility given how close these sides were in the cup.
What worries me is Sassuolo’s attacking quality. Berardi, Esposito and Laurienté can hurt any defence, and Sassuolo have scored in every league game. If they score first, Frosinone may struggle to come back. But Frosinone’s home form and Sassuolo’s away record tip it towards the hosts for me.
My main bet is Frosinone Draw No Bet at 1.71 with Winz. My correct-score pick is 2-1.